Aid in the differential diagnosis of adenovirus, human metapneumonvirus, and rhinovirus infections by nucleic acid amplification obtained from individuals exhibiting signs and symptoms of a respiratory tract infection.

Methodology

Multiplex real-time PCR (RT-PCR)

Reference Interval

Not detected

Providers can order this test as part of a Respiratory Pathogen Profile

Limitations

This test does not differentiate Adenovirus subtypes (i.e. 1-58), human Metapneumovirus subtypes (i.e., A1, A2, B1, B2) or Rhinovirus species (i.e., Rhinovirus A, Rhinovirus B or Rhinovirus C); additional testing is required to differentiate any specific Adenovirus subtypes, human Metapneumovirus subtypes or specific Rhinovirus species in consultation with local public health departments.

There is a risk of hMPV or AdV false positive results in samples containing high Rhinovirus viral content.

• Insurance

• If insurance is not billed, patients are responsible for the cost for testing - $200. Pay for test here.

1-2 days

Turnaround time is defined as the usual number of days from the date of receipt of a specimen to the laboratory. Testing schedules may vary.

Submit one specimen per specimen source on tests requested

Collection

Collect Nasopharyngeal swab specimens according to standard technique using a polyester-, rayon-, or nylon-tipped swab. Immediately place the swab specimen into 3 mL of VTM.

The following types of VTM were verified for use.

• BD Universal Viral Transport Medium

Nasopharyngeal (NP) swab in a 3mL of VTM: BD Universal Viral Transport Medium

Volume

3 mL

Storage Requirements

Maintain specimen at 2°C to 8°C up to 96 hours.

Rejection Criteria

Samples collected incorrectly (ie. Swabs other than NPs, transport media other than the acceptable media listed above, cotton swab, specimens stored at wrong temperature, etc.); samples transported incorrectly; unlabeled or improperly labelled specimens; quantity of transport media not sufficient for testing; leaking or co-mingled samples.)

Sample Report